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Hereditary Spastic Paraplegias: From Genes to Axons to Trials

  • Toronto Western Hospital 399 Bathurst Street Toronto, ON, M5T 2S6 Canada (map)

Dr. Renato Munhoz is an Associate Professor of Neurology at the University of Toronto and a co-lead of Krembil Brain Institute Education.

He has focused most of his efforts on clinical management of patients with ataxia and other movement disorders. His team is currently working on the protocol for the assessment of symmetry of distribution of motor symptoms and signs in genetically determined ataxias, which are caused by certain defective genes that make abnormal proteins, and are expressed differently depending on the gene. This protocol will be part of a study that will, for the first time, help us understand how and why hereditary ataxias are prone to causing motor impairments.